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Note: In lieu of an abstract, this is the article's first page. Cited By. This article is cited by 71 publications. Ahmed F. Black, Nicola L.
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Chichibabin pyridine synthesis
The elementary contributing steps of the reaction mechanism can be classified as more familiar name reactions, including an imine synthesis , a base-catalyzed aldol condensation , and initiating the ring-synthesis step, a Michael reaction. Showing detailed curved-arrow electron pushing steps, formal charges, and categorized steps of the reaction. Alkyl-substituted pyridines show widespread uses among multiple fields of applied chemistry, including the polymer and pharmaceutical industries. For example, 2-methylpyridine , 4-methylpyridine and 2-ethylmethylpyridine exhibit widespread use in syntheses of latexes , ion-exchange matrixes , and photography materials. One of the chief limitations of practical application of the traditional Chichibabin pyridine synthesis is its consistently low product yield.