DEDIFFERENTIATION TRANSDIFFERENTIATION AND REPROGRAMMING THREE ROUTES TO REGENERATION PDF

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Either your web browser doesn't support Javascript or it is currently turned off. In the latter case, please turn on Javascript support in your web browser and reload this page. Nature reviews. Read article at publisher's site DOI : Brockes JP , Kumar A. Biomol Ther Seoul , 28 1 , 01 Jan G3 Bethesda , 9 12 , 03 Dec Diabetes , 68 10 , 01 Oct Cited by: 0 articles PMID: Cited by 2 articles PMID: Stem Cell Res Ther , 10 1 , 23 Sep To arrive at the top five similar articles we use a word-weighted algorithm to compare words from the Title and Abstract of each citation.

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Abstract Available from publisher site using DOI. A subscription may be required. Aiguader, 88, Barcelona, Spain. Search articles by 'Chris Jopling'. Jopling C 1 ,. Boue S ,. Izpisua Belmonte JC. Affiliations 1 author 1. Center of Regenerative Medicine in Barcelona, Dr. Share this article Share with email Share with twitter Share with linkedin Share with facebook.

This can potentially be accomplished using the processes of dedifferentiation, transdifferentiation or reprogramming. Recent advances have shown that the addition of a group of genes can not only restore pluripotency in a fully differentiated cell state reprogramming but can also induce the cell to proliferate dedifferentiation or even switch to another cell type transdifferentiation.

Current research aims to understand how these processes work and to eventually harness them for use in regenerative medicine. Cell Biol. Title not supplied Wolff Org. Reprogramming and differentiation in mammals: motifs and mechanisms. Heart regeneration in zebrafish. Activation of Notch signaling pathway precedes heart regeneration in zebrafish.

Zebrafish heart regeneration occurs by cardiomyocyte dedifferentiation and proliferation. Transcriptomics approach to investigate zebrafish heart regeneration. Gene expression analysis of zebrafish heart regeneration. A dynamic epicardial injury response supports progenitor cell activity during zebrafish heart regeneration.

Show 10 more references 10 of Smart citations by scite. The number of the statements may be higher than the number of citations provided by EuropePMC if one paper cites another multiple times or lower if scite has not yet processed some of the citing articles. Explore citation contexts and check if this article has been supported or contradicted. Coordinated removal of repressive epigenetic modifications during induced reversal of cell identity.

An overview on small molecule-induced differentiation of mesenchymal stem cells into beta cells for diabetic therapy. Dedifferentiation, transdifferentiation, and reprogramming: future directions in regenerative medicine.

Reprogramming and transdifferentiation shift the landscape of regenerative medicine. Chemical transdifferentiation: closer to regenerative medicine.

Dedifferentiation and reprogramming: origins of cancer stem cells. This website requires cookies, and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our privacy notice and cookie policy. I agree, dismiss this banner. Wicket Ajax Debug Window drag me here.

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Dedifferentiation, Transdifferentiation and Reprogramming: Three Routes to Regeneration

Thank you for visiting nature. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser or turn off compatibility mode in Internet Explorer. In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript. A Nature Research Journal. The ultimate goal of regenerative medicine is to replace lost or damaged cells. This can potentially be accomplished using the processes of dedifferentiation, transdifferentiation or reprogramming.

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Dedifferentiation, transdifferentiation and reprogramming: three routes to regeneration.

The ultimate goal of regenerative medicine is to replace lost or damaged cells. This can potentially be accomplished using the processes of dedifferentiation, transdifferentiation or reprogramming. Recent advances have shown that the addition of a group of genes can not only restore pluripotency in a fully differentiated cell state reprogramming but can also induce the cell to proliferate dedifferentiation or even switch to another cell type transdifferentiation. Current research aims to understand how these processes work and to eventually harness them for use in regenerative medicine. This site needs JavaScript to work properly.

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