ANOMALIES DU SPERMOGRAMME PDF

We'd like to understand how you use our websites in order to improve them. Register your interest. Vingt pour cent des patients ont des pathologies du tractus respiratoire. Conventional semen analysis sperm count is limited to examination of spermatozoa at a magnification of x1,, which may be insufficient in rare situations. Electron microscopy sperm examination allows high-power x , analysis of sperm organelles and quantification of abnormalities of the constituents involved in sperm mobility and fertility potential. All of these anomalies are associated with primary infertility.

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We'd like to understand how you use our websites in order to improve them. Register your interest. Vingt pour cent des patients ont des pathologies du tractus respiratoire. Conventional semen analysis sperm count is limited to examination of spermatozoa at a magnification of x1,, which may be insufficient in rare situations. Electron microscopy sperm examination allows high-power x , analysis of sperm organelles and quantification of abnormalities of the constituents involved in sperm mobility and fertility potential.

All of these anomalies are associated with primary infertility. Globozoospermia and pinheads can be detected by light microscopy. Electron microscopy sperm morphology examination precisely identifies and quantifies sperm abnormalities.

Pathological phenotypes have a heterogeneous expression. The organelles of spermatozoa other than those primarily involved in the pathological phenotype may also present alterations. Globozoospermia is generally characterized by the absence of elongation of the nucleus, and absence of the acrosome and the post-acrosomal region. The implantation fossa and basal plate are generally missing in decapitated spermatozoa.

Asthenospermia may be an indication for electron microscopy sperm examination when it is not associated with necrospermia. In primary ciliary dyskinesia PCD , spermatozoa are often immobile and present a normal morphology on light microscopy. Apart from the complete form with absent axoneme, incomplete forms are also observed with absence of the dynein arms, peripheral doublets, microtubules. These phenotypes have a low prevalence in the population of infertile men.

A familial incidence, parental consanguinity, and a high incidence in certain geographical regions are frequently reported, suggesting the existence of one or several genetic mechanisms. Despite the limited state of knowledge at the present time, couples must be informed about the possible transmission of the phenotype to their descendants. All men with these phenotypes are spontaneously infertile.

The only alternative fertilization technique is intracytoplasmic sperm injection ICSI. According to the literature and our own experience, the results of ICSI with sperm presenting these phenotypes are poorer than those of ICSI in general. Electron microscopy is not only a diagnostic tool in severe male infertility, but also a prognostic indicator of the success of management by ICSI, which must be evaluated for each case.

Download to read the full article text. Science, , — Immotile cilia syndrome: past, present, and prospects for the future. Thorax, , 53, — USA, , 99, — Google Scholar.

Origin, characterisation and fertility potential of abnormal sperm phenotypes in infertile men. Update, , 5: — Andrologia, , — DAM A. Update, , 63— Andrologie, , 5: 15— Genet, , — Berlin, Grosse Verlag, KIM S. LIU J. MIKI K. Ultrastructural and meiotic segregation study. RAWE V. Chest, , 80 6 Suppl. Andrology, , 3: — Care Med. Download references. Reprints and Permissions. Mitchell, V. Download citation. Received : 15 November Accepted : 15 November Issue Date : March Search SpringerLink Search.

Download PDF. Abstract Conventional semen analysis sperm count is limited to examination of spermatozoa at a magnification of x1,, which may be insufficient in rare situations. References 1. Calmette, Bd du Pr J. You can also search for this author in PubMed Google Scholar. View author publications. Rights and permissions Reprints and Permissions. About this article Cite this article Mitchell, V.

FIKE SHP 10-051 PDF

Indications de la recherche des anticorps anti-spermatozoïdes

Le sperme, obtenu au laboratoire par masturbation, a servi aux analyses macroscopiques et microscopiques. Infertility is a public health problem in developing countries and its expensive exploration in male relies mainly on the cytology of sperm, without association with seminal biochemistry. Thus, a relationship between spermogram abnormalities and alpha-glucosidase, fructose and seminal plasma citrate has been investigated, in order to justify or not the rarity of sperm biochemistry. All patients admitted consecutively during the study period, to perform a spermogram for infertility assessment, were included. Sperm, obtained in the laboratory by masturbation, was used for macroscopic and microscopic analyzes. Neutral alpha-glucosidase, fructose and citrate were obtained in seminal plasma. Univariate analysis made it possible to choose the parameters to be included in the factorial analysis between cytological and biochemical parameters.

FORM SSA 7004 PDF

We'd like to understand how you use our websites in order to improve them. Register your interest. The clinical significance of antisperm antibodies ASA is highly controversial. A significant percentage of infertile men and women present immunity to spermatozoa, suggesting that ASA may interfere with the fertilizing capacity. ASA can act negatively on sperm parameters, sperm-cervical mucus interaction, gamete fusion and possibly also on the first step of embryonic development. ASA are present in approximately 2. The pathogenesis of immunity to spermatozoa had not been fully elucidated: breakdown of normal protective mechanisms, i.

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